Protein complex detection using interaction reliability assessment and weighted clustering coefficient

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

comparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods

هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...

15 صفحه اول

Generalizations of the clustering coefficient to weighted complex networks.

The recent high level of interest in weighted complex networks gives rise to a need to develop new measures and to generalize existing ones to take the weights of links into account. Here we focus on various generalizations of the clustering coefficient, which is one of the central characteristics in the complex network theory. We present a comparative study of the several suggestions introduce...

متن کامل

Topic Detection and Tracking using idf-Weighted Cosine Coefficient

The goal of TDT Topic Detection and Tracking is to develop automatic methods of identifying topically related stories within a stream of news media. We describe approaches for both detection and tracking based on the well-known idf -weighted cosine coefficient similarity metric. The surprising outcome of this research is that we achieved very competitive results for tracking using a very simple...

متن کامل

Integrated Reliability-Assessment for Protein-Protein Interaction Data

Interaction among genes and gene products has a major role in many cellular processes. Obtaining an accurate picture of protein-protein interactions is one of the major challenges to the systematic understanding of cellular activity. While there are reliable but time-consuming experimental techniques to determine interactions, there have been developed a variety of high-throughput methods to ob...

متن کامل

Protein Complex Detection via Weighted Ensemble Clustering Based on Bayesian Nonnegative Matrix Factorization

Detecting protein complexes from protein-protein interaction (PPI) networks is a challenging task in computational biology. A vast number of computational methods have been proposed to undertake this task. However, each computational method is developed to capture one aspect of the network. The performance of different methods on the same network can differ substantially, even the same method m...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: BMC Bioinformatics

سال: 2013

ISSN: 1471-2105

DOI: 10.1186/1471-2105-14-163